Bone involvement in leprosy: Early changes

Bone changes in leprosy under sulfone therapy.

Much success has been reported in the treatment of leprosy within the past seven years from those countries where the sulfone drugs promin, diasone and promizole have been used (1-6). Similarly encouraging therapeutic results have been reported within recent months for another related sulfone called sulfetrone (7). All of these reports seem to indicate that, thus far, the chief value of the sul...

Bone Involvement in Neuroblastoma

Pupil cycle time and early autonomic involvement in ocular leprosy.

Ocular complications of leprosy patients often develop insidiously and with few if any symptoms. This study involves measurement of the pupil cycle time (PCT) to evaluate the autonomic nerve system of the iris to determine the presence of subclinical intraocular involvement. The study included 19 lepromatous (LL), 19 borderline lepromatous (BL), and five borderline tuberculoid (BT) leprosy pati...

[Nail involvement in leprosy].

Leprosy, a disease caused by Mycobacterium leprae, primarily affects the skin and nerves, but the nails are also involved in as many as 3 out of 4 patients .The factors that trigger nail changes in leprosy are numerous and include repeated trauma, neuropathy, vascular impairment, infections, lepra reactions, and the drugs used to manage the disease. The changes most often reported include subun...

Hepatic involvement in lepromatous leprosy.

Hepatic involvement in a lepromatous leprosy (LL) patient is reported. The serum concentrations of aminotransferases were much higher than previously described in the leprosy literature. Other causes for hepatic damage were ruled out. Such hepatic involvement and elevation of aminotransferases have never been described in leprosy.